Personalising health and care ............................................................................................................... 7
Understanding health, ageing and disease ........................................................................................... 7
PHC 1 – 2014: Understanding health, ageing and disease: determinants, risk factors and pathways ........................................................................................................................................................ 7
PHC 2 – 2015: Understanding diseases: systems medicine ............................................................ 8
PHC 3 - 2015: Understanding common mechanisms of diseases and their relevance in co-morbidities ...................................................................................................................................... 9
Effective health promotion, disease prevention, preparedness and screening ................................... 10
PHC 4 – 2015: Health promotion and disease prevention: improved inter-sector co-operation for environment and health based interventions ................................................................................. 10
PHC 5 – 2014: Health promotion and disease prevention: translating ‘omics’ into stratified approaches .................................................................................................................................... 11
PHC 6 – 2014: Evaluating existing screening and prevention programmes ................................. 12
PHC 7 – 2014: Improving the control of infectious epidemics and foodborne outbreaks through rapid identification of pathogens (see also societal challenge 2) .................................................. 13
PHC 8 – 2014: Vaccine development for poverty-related and neglected infectious diseases: Tuberculosis ................................................................................................................................. 15
PHC 9 – 2015: Vaccine development for poverty-related and neglected infectious diseases: HIV/AIDS .................................................................................................................................... 16
Improving diagnosis .......................................................................................................................... 18
PHC 10 – 2014: Development of new diagnostic tools and technologies: in vitro devices, assays and platforms ................................................................................................................................ 18
PHC 11 – 2015: Development of new diagnostic tools and technologies: in vivo medical imaging technologies .................................................................................................................................. 19
PHC 12 – 2014/2015: Clinical research for the validation of biomarkers and/or diagnostic medical devices ............................................................................................................................. 20
Innovative treatments and technologies ............................................................................................ 22
PHC 13 – 2014: New therapies for chronic non-communicable diseases ..................................... 22
PHC 14 – 2015: New therapies for rare diseases .......................................................................... 23
PHC 15 – 2014/2015: Clinical research on regenerative medicine ............................................... 24
PHC 16 – 2015: Tools and technologies for advanced therapies .................................................. 25
PHC 17 – 2014: Comparing the effectiveness of existing healthcare interventions in the elderly 26
PHC 18 – 2015: Establishing effectiveness of health care interventions in the paediatric population ..................................................................................................................................... 28
Advancing active and healthy ageing ................................................................................................ 29

PHC 19 – 2014: Advancing active and healthy ageing with ICT: Service robotics within assisted living environments ....................................................................................................................... 29
PHC 20 – 2014: Advancing active and healthy ageing with ICT: ICT solutions for independent living with cognitive impairment .................................................................................................. 30
PHC 21 – 2015: Advancing active and healthy ageing with ICT: Early risk detection and intervention ................................................................................................................................... 31
PHC 22 – 2015: Promoting mental wellbeing in the ageing population ....................................... 32
Integrated, sustainable, citizen-centred care ...................................................................................... 33
PHC 23 – 2014: Developing and comparing new models for safe and efficient, prevention oriented health and care systems: .................................................................................................. 33
PHC 24 – 2015: Piloting personalised medicine in health and care systems ................................ 34
PHC 25 – 2015: Advanced ICT systems and services for Integrated Care ................................... 35
PHC 26 – 2014: Self-management of health and disease: citizen engagement and mHealth ....... 37
PHC 27 – 2015: Self-management of health and disease and patient empowerment supported by ICT ............................................................................................................................................... 40
PHC 28 – 2015: Self-management of health and disease and decision support systems based on predictive computer modelling used by the patient him or herself ............................................... 42
PHC 29 – 2015: Public procurement of innovative eHealth services ........................................... 43
Improving health information, data exploitation and providing an evidence base for health policies and regulation ................................................................................................................................... 45
PHC 30 – 2015: Digital representation of health data to improve disease diagnosis and treatment ...................................................................................................................................................... 45
PHC 31 – 2014: Foresight for health policy development and regulation .................................... 46
PHC 32 – 2014: Advancing bioinformatics to meet biomedical and clinical needs ..................... 47
PHC 33 – 2015: New approaches to improve predictive human safety testing ............................ 49
PHC 34 – 2014: eHealth interoperability ...................................................................................... 50
CONDITIONS FOR THIS CALL .............................................................................................................. 54
Co-ordination activities ....................................................................................................................... 63
HCO 1 – 2014: Support for the European Innovation Partnership on Active and Healthy Ageing ...................................................................................................................................................... 63
HCO 2 – 2014: Joint Programming: Coordination Action for the Joint Programming Initiative (JPI) "More Years, Better Lives - the Challenges and Opportunities of Demographic Change" .. 64
HCO 4 – 2014: Support for international infectious disease preparedness research ..................... 66
HCO 5 – 2014: Global Alliance for Chronic Diseases: prevention and treatment of type 2 diabetes ......................................................................................................................................... 67
HCO 6 – 2015: Global Alliance for Chronic Diseases. Prevention and treatment of lung diseases ...................................................................................................................................................... 70

HCO 7 – 2014: ERA-NET: Establishing synergies between the Joint Programming on Neurodegenerative Diseases Research and Horizon 2020 ............................................................ 74
HCO 8 – 2014: ERA-NET: Aligning national/regional translational cancer research programmes and activities ................................................................................................................................. 76
HCO 9 – 2014: ERA-NET: Systems medicine to address clinical needs ...................................... 77
HCO 10 – 2014: ERA NET: Rare Disease research implementing IRDiRC objectives ............... 79
HCO 11 – 2015: ERA-NET: Collaboration and alignment of national programmes and activities in the area of brain-related diseases and disorders of the nervous system .................................... 80
HCO 12 – 2015: ERA-NET: Antimicrobial Resistance ................................................................ 81
HCO 13 – 2015: ERA-NET: Cardiovascular disease .................................................................... 83
HCO 14 – 2014: Bridging the divide in European health research and innovation ...................... 85
HCO 15 – 2014: Mobilisation and mutual learning action plan .................................................... 86
HCO 16 – 2014: National Contact Points ..................................................................................... 86
HCO 17 – 2015: Towards sustainability and globalisation of the Joint Programming Initiative on Neurodegenerative Diseases .......................................................................................................... 88
CONDITIONS FOR THIS CALL .............................................................................................................. 90
Fast track to innovation pilot ......................................................................................................... 93
Other actions ...................................................................................................................................... 94
HOA 1 – 2014/2015: Subscription fee: Human Frontier Science Programme Organisation ........ 94
HOA 2 – 2014/2015: Tenders for programme evaluation, studies and impact assessment, Scientific Panel for Health, and for conferences, events and outreach activities. ......................... 94
HOA 3 – 2014/2015: Presidency events - eHealth ........................................................................ 95
HOA 4 – 2014/15: Independent experts assisting in proposal evaluations and assessment, and project reviews .............................................................................................................................. 95
HOA 5 – 2014: Grant to the Global Alliance for Chronic Diseases ............................................. 96
HOA 6 – 2014: Stem cell research outreach ................................................................................. 96
HOA 7 – 2015: eHealth Inducement Prize: Food scanner ............................................................ 98
HOA 8 – 2015: Inducement Prize: An innovative test to reduce the use of antibiotics in the management of upper respiratory tract infection. .......................................................................... 99
Budget ............................................................................................................................................ 101